Beckervordersandforth Lab
Astrocyte Diversity and Dynamics
Nick Chalmers
BIOGRAPHY:
2021 - Present PhD Student (GRK 2162), Institute of Biochemistry, FAU Erlangen-Nürnberg
2018 - 2020 Biomedical Engineering (Master of Engineering), Colorado State University
2013- 2015 Integrative Physiology (Bachelor of Science), University of Colorado, Boulder
PUBLICATIONS:
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Burch, A. M., Garcia, J. D., O’Leary, H., Haas, A., Orfila, J. E., Tiemeier, E., ... & Herson, P. S. (2024). TRPM2 and CaMKII signaling drives excessive GABAergic synaptic inhibition following ischemia. Journal of Neuroscience, 44(19).​ doi: 10.1523/JNEUROSCI.1762-23.2024
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Schneider, Y., Gauer, C., Andert, M., Hoffmann, A., Riemenschneider, M. J., Krebs, W., ... & Winkler, J. (2024). Distinct forebrain regions define a dichotomous astrocytic profile in multiple system atrophy. Acta Neuropathologica Communications, 12(1), 1. doi: 10.1186/s40478-023-01699-3
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Chalmers, N., Masouti, E., & Beckervordersandforth, R. (2024). Astrocytes in the adult dentate gyrus—balance between adult and developmental tasks. Molecular Psychiatry, 1-10. doi: 10.1038/s41380-023-02386-4
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Karpf, J., Unichenko, P., Chalmers, N., Beyer, F., Wittmann, M. T., Schneider, J., ... & Beckervordersandforth, R. (2022). Dentate gyrus astrocytes exhibit layer-specific molecular, morphological and physiological features. Nature Neuroscience, 1-13. doi: 10.1038/s41593-022-01192-5
Dietz, R. M., Orfila, J. E., Chalmers, N., Minjarez, C., Vigil, J., Deng, G., ... & Herson, P. S. (2021). Functional Restoration following Global Cerebral Ischemia in Juvenile Mice following Inhibition of Transient Receptor Potential M2 (TRPM2) Ion Channels. Neural plasticity, 2021. doi: 10.1155/2021/8774663
Olivia R. Buonarati, Sarah G. Cook, Dayton J. Goodell, Nicholas E. Chalmers, …& Bayer, U. K. (2020). CaMKII versus DAPK1 Binding to GluN2B in Ischemic Neuronal Cell Death after Resuscitation from Cardiac Arrest. Cell Reports, 30(1), 1-8. doi: 10.1016/j.celrep.2019.11.076
Chalmers, N. E., Yonchek, J., Steklac, K. E., Ramsey, M., Bayer, K. U., Herson, P. S., & Quillinan, N. (2019). Calcium/Calmodulin-Dependent Kinase (CaMKII) Inhibition Protects Against Purkinje Cell Damage Following CA/CPR in Mice. Molecular Neurobiology, 1-9. doi: 10.1007/s12035-019-01765-9
Dietz, R. M., Cruz-Torres, I., Orfila, J. E., Patsos, O. P., Shimizu, K., Chalmers, N., ... & Herson, P. S. (2019). Reversal of Global Ischemia-Induced Cognitive Dysfunction by Delayed Inhibition of TRPM2 Ion Channels. Translational Stroke Research, 1-13. doi: 10.1007/s12975-019-00712-z
Orfila, J. E., McKinnon, N., Moreno, M., Deng, G., Chalmers, N., Dietz, R. M., ... & Quillinan, N. (2018). Cardiac arrest induces ischemic long-term potentiation of hippocampal CA1 neurons that occludes physiological long-term potentiation. Neural Plasticity, 2018. doi: 10.1155/2018/9275239
Dietz, R. M., Orfila, J. E., Rodgers, K. M., Patsos, O. P., Deng, G., Chalmers, N., ... & Herson, P. S. (2018). Juvenile cerebral ischemia reveals age-dependent BDNF–TrkB signaling changes: Novel mechanism of recovery and therapeutic intervention. Journal of Cerebral Blood Flow & Metabolism, 38(12), 2223-2235. doi: 10.1177/0271678X18766421